Pacific Blue(TM) anti-human CD4 317423 from BioLegend

Product Specs
ItemPacific Blue(TM) anti-human CD4
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number317423
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
CloneOKT4
HostMouse
ApplicationsFlow Cytometry (FC)
Conjugate/TagPacific Blue
Quantity25 µg
IsotypeIgG2b, Kappa
ReactivityHuman, Cynomolgus, Rhesus
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
Concentration0.50 mg/mL
Formattest size: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
µg sizes: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
ClonalityMonoclonal
ImmunogenHuman peripheral T cells
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus MacaquesmBioAugust 31, 2021Hasenkrug KJ, Feldmann F, Myers L, Santiago ML, Guo K, Barrett BS, Mickens KL, Carmody A, Okumura A, Rao D, et al.(FITC)–anti-CD8 (DK25, Millipore FCMAB176F, lot 3398058), and Pacific Blue–anti-CD4 (OKT4; BioLegend 317424, lot B258189) in 2% FBS–PBS supplemented with brilliant stain buffer (BD Biosciences). Intracellular

(2) COVID-19 convalescent plasma as long-term therapy in immunodeficient patients?Transfusion Clinique et BiologiqueAugust 1, 2021D. Rnjak et al.Coulter Panel 3,Panel 3,Panel 3 CD45 FITC,347463,BD Biosciences CD3 PE,345765,BD Biosciences CD4 PB,317424,Biolegend CD38 PE-Cy5,555461,BD Biosciences CD279 PE-Cy7,329918,Biolegend CD14 APC,555399,BD Biosciences Antibody

(3) Recovery from acute SARS-CoV-2 infection and development of anamnestic immune responses in T cell-depleted rhesus macaquesbioRxiv : the preprint server for biologyApril 4, 2021Hasenkrug KJ, Feldmann F, Myers L, Santiago ML, Guo K, Barrett BS, Mickens KL, Carmody A, Okumura A, Rao D, et al.0133645), FITC-anti-CD8 (DK25, Millipore FCMAB176F Lot 3398058), and Pacific Blue-anti-CD4 (OKT4, BioLegend 317424 Lot B258189) in 2% FBS PBS supplemented with Brilliant Stain Buffer (BD Biosciences). Intracellular

(4) CD8+CD39+ T Cells Mediate Anti-Tumor Cytotoxicity in Bladder CancerOncoTargets and TherapyMarch 25, 2021Wenjie Zhu, Zihan Zhao, Baofu Feng, Wenhao Yu, Ji Li, Hongqian Guo, Rong Yang

(5) Improved Detection of HIV Gag p24 Protein Using a Combined Immunoprecipitation and Digital ELISA MethodFrontiers in microbiologyJanuary 1, 2021Wu G, Cheney C, Huang Q, Hazuda DJ, Howell BJ, Zuck P.MAB375-500) was used as capture antibody, and anti-CD4 monoclonal antibody OKT4 from Biolegend (Cat# 317424) was used as detection antibody. OKT4 antibody was conjugated with alkaline phosphatase (AP) according

(6) HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple SclerosisCellNovember 25, 2020Wang J, Jelcic I, Mühlenbruch L, Haunerdinger V, Toussaint NC, Zhao Y, Cruciani C, Faigle W, Naghavian R, Foege M, et al.

(7) Complement-activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cellsThe Journal of clinical investigationJuly 1, 2020Xie CB, Jiang B, Qin L, Tellides G, Kirkiles-Smith NC, Jane-Wit D, Pober JS.were harvested and stained with Fixable Viability Dye (eBioscience, 65-0865-14), anti–human CD4 (BioLegend, 317424), anti–human CD8 (eBioscience, 48-0086-42), and anti–human HLA-DR (BioLegend, 307676). For intracellular

(8) Phenotype and functionality of follicular helper T cells in patients with acute dengue infectionJournal of biomedical scienceApril 8, 2020Wijesinghe A, Gamage J, Goonewardena H, Gomes L, Jayathilaka D, Wijeratne DT, de Alwis R, Jeewandara C, Wijewickrama A, Ogg GS, et al.

(9) Vitamin D supplementation decreases immune activation and exhaustion in HIV-1-infected youthAntiviral therapyJanuary 1, 2018Eckard AR, O'Riordan MA, Rosebush JC, Lee ST, Habib JG, Ruff JH, Labbato D, Daniels JE, Uribe-Leitz M, Tangpricha V, et al.

(10) Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid RecruitmentCancer cellDecember 11, 2017Turaj AH, Hussain K, Cox KL, Rose-Zerilli MJJ, Testa J, Dahal LN, Chan HTC, James S, Field VL, Carter MJ, et al.

(11) Neurocognitive dysfunction in HIV-infected youth: investigating the relationship with immune activationAntiviral therapyJanuary 1, 2017Eckard AR, Rosebush JC, O'Riordan MA, Graves CC, Alexander A, Grover AK, Lee ST, Habib JG, Ruff JH, Chahroudi A, et al.

(12) A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6PloS oneJanuary 1, 2017Robert R, Juglair L, Lim EX, Ang C, Wang CJH, Ebert G, Dolezal O, Mackay CR.

(13) Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative ColitisGastroenterologyFebruary 1, 2016Tew GW, Hackney JA, Gibbons D, Lamb CA, Luca D, Egen JG, Diehl L, Eastham Anderson J, Vermeire S, Mansfield JC, et al.

(14) Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected MacaquesJournal of virologySeptember 1, 2015Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, et al.

(15) Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infectionNature communicationsAugust 18, 2015Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, et al.

(16) Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapyThe Journal of infectious diseasesMarch 1, 2015Estes JD, Reilly C, Trubey CM, Fletcher CV, Cory TJ, Piatak M Jr, Russ S, Anderson J, Reimann TG, Star R, et al.

(17) Vaccination Expands Antigen-Specific CD4+ Memory T Cells and Mobilizes Bystander Central Memory T CellsPloS oneJanuary 1, 2015Li Causi E, Parikh SC, Chudley L, Layfield DM, Ottensmeier CH, Stevenson FK, Di Genova G.

(18) Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaquesJournal of virologyApril 1, 2014McGary CS, Cervasi B, Chahroudi A, Micci L, Taaffe J, Meeker T, Silvestri G, Davenport MP, Paiardini M.

(19) Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaquesPLoS pathogensMarch 1, 2014Chahroudi A, Cartwright E, Lee ST, Mavigner M, Carnathan DG, Lawson B, Carnathan PM, Hashempoor T, Murphy MK, Meeker T, et al.

(20) Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infectionThe Journal of infectious diseasesMarch 15, 2013Tabb B, Morcock DR, Trubey CM, Quiñones OA, Hao XP, Smedley J, Macallister R, Piatak M Jr, Harris LD, Paiardini M, et al.

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Pacific Blue(TM) anti-human CD4 from BioLegend

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Pacific Blue(TM) anti-human CD4 from BioLegend

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